Researchers at the University of California, San Diego School of Medicine have developed a groundbreaking investigational drug that directly targets fat production in the liver, offering a potential breakthrough for people with advanced fatty liver disease.
A New Approach to Treatment
The drug is designed to treat metabolic dysfunction-associated steatohepatitis (MASH), a severe form of fatty liver disease linked to obesity and type 2 diabetes. MASH can progress to cirrhosis, liver failure, or even liver cancer if left untreated. While current treatments largely focus on lifestyle changes, this new therapy targets the underlying fat production mechanisms in the liver itself.
Promising Results
In preclinical studies, the drug significantly reduced liver fat accumulation and improved key liver function markers. These findings suggest that the therapy could be a game-changer for millions of individuals affected by MASH, providing hope for a more effective, targeted treatment.
Next Steps
The research team plans to begin clinical trials to assess the drug’s safety and efficacy in humans. If successful, this treatment could become the first therapy specifically designed to target the root causes of fatty liver disease, marking a major advancement in liver health and hepatology research.
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